Selected Publications
See full list in google scholar.
Simons, Y.B., Mostafavi, H., Smith, C.J., Pritchard, J.K. and G. Sella (2024) Simple scaling laws control the genetic architectures of human complex traits. In revision.
Baker, Z., Przeworski, M. and G. Sella (2023) Down the Penrose stairs: How selection for fewer recombination hotspots maintains their existence. eLife 12: e83769.
Murphy, D.A., Elyashiv, E., Amster, G. and G. Sella (2022) Broad-scale variation in human genetic diversity levels is predicted by purifying selection on coding and non-coding elements. eLife 11: e76065.
Hayward, L. K. and G. Sella (2022) Polygenic adaptation after a sudden change in environment. eLife11: e66697.
Milligan, W.R., Amster, G. and G. Sella (2022) The impact of genetic modifiers on variation in germline mutation rates within and among human populations. Genetics 221: iyac087.
Milligan, W.R., Fuller, Z.L., Agarwal, I., Eisen, M.B., Przeworski, M., and G. Sella (2020). Impact of essential workers in the context of social distancing for epidemic control. PLoS ONE 16: e0255680.
Amster, G., Murphy, D.A., Milligan, W.R. and G. Sella (2020). Changes in life history and population size can explain relative neutral diversity levels on X and autosomes in extant human populations. PNAS 117: 20063-69.
Amster, G. and G. Sella (2020). Life history effects on neutral diversity levels of autosomes and sex chromosomes.
Sella, G. and N. Barton (2019). Thinking about the evolution of complex traits in the era of GWAS. Annual Reviews in Genomics and Human Genetics 20: 461-493.
Fuller, Z., Berg, J.J., Mostafavi, H., Sella, G. and M. Przeworski (2019). Measuring intolerance to mutation in human genetics. Nature Genetics 51: 772–776.
Simons, Y.B., Bullaughey, K., Hudson, R. and G. Sella (2018). A population genetic interpretation of GWAS findings for human quantitative traits. PLoS Biol 16: e2002985.
Simons, Y.B. and G. Sella (2016). The impact of recent population history on the deleterious mutation load in humans and close evolutionary relatives. Curr Opin Genet Dev 41: 150-158.
Elyashiv, E., Sattath S., Hu, T., McVicker, G., Strutsovsky, A., Andolfatto, P., Coop, G. and G. Sella (2016). A genomic map of the effects of linked selection in Drosophila. PLoS Genetics 12: e1006130.
Amster, G. and G. Sella (2016). Life history effects on the molecular clock of autosomes and sex chromosomes. PNAS 113: 1588-1593.
Simons, Y.B., Turchin, M., Pritchard, J.K.+, and G. Sella+ (2014). The deleterious mutation load is insensitive to recent population history. Nature Genetics 46: 220–224. +Joint senior authors.
Hernandez, R.D., Kelley, J.L., Elyashiv, E., Melton, S.C., Auton, A., McVean, G., 1000 Genomes Project, Sella, G.* and M. Przeworski* (2011). Classic selective sweeps were rare in recent human evolution. Science 331: 920-924. * Contributed equally.
Sattath, S., Elyavish, E., Kolodny, O., Rinott, Y. and G. Sella (2011). Pervasive adaptive protein evolution apparent from diversity patterns around amino-acid substitutions in Drosophila simulans. PLoS Genetics 7: e1001302.
Sella, G., Petrov, D.A., Przeworski, M. and P. Andolfatto (2009). Evidence for Pervasive Natural Selection in Drosophila? PLoS Genetics 5: e1000495.
Macpherson, M.*, Sella, G.*, Davis, J.C. and D.A. Petrov (2007). Genome-wide spatial correspondence between non-synonymous divergence and neutral polymorphism reveals extensive adaptation in Drosophila. Genetics 177: 2083-89. *Joint first authors.
Sella, G. and D.H. Ardell (2006). The Coevolution of Genes and Genetic Codes: Crick’s Frozen Accident Revisited. Journal of Molecular Evolution 63: 297-313.
Sella, G. and A.E. Hirsh (2005). The Application of Statistical Physics to Evolutionary Biology. PNAS 102: 9541-9546.